• br Conflicts of interest br Acknowledgements This

  2019-07-24

  

  Conflicts of interest Acknowledgements This work was supported by funding from Young Sanjin Scholars Distinguished Professor, the Aid Program for Innovation Research Team in Shanxi Agricultural University (CXTD201201), and the Special Fund for Agro-scientific Research in the Public Interest of

• 3-Methyladenine where Investigations of mice lacking up to t

  2019-07-24

  

  Investigations of mice lacking up to three CDKs identified the mitosis-regulating kinase CDK1 as the main essential component for the cell cycle, whereas ablation of other 3-Methyladenine where regulators such as CDK2, CDK4, or CDK6 did not result in defective proliferation 12, 13. Mouse models and

• Prostaglandins PGs are lipid mediators that exhibit a variet

  2019-07-24

  

  Prostaglandins (PGs) are lipid mediators that exhibit a variety of physiological properties by interacting specific G protein-coupled receptors (GPCRs) [10]. PGD2 is synthesized from PGH2 through two distinct PGD synthases; lipocalin-type PGD synthase (L-PGDS) and hematopoietic PGD synthase (H-PGDS)

• br Method br Results br

  2019-07-24

  

  Method Results Discussion In this cross-sectional study, we investigated the relationship between the COMT ValMet polymorphism and age on regional cortical thickness in healthy adults across the lifespan. The mesocortical pathway was of primary interest because of its projections from the v

• As demonstrated by Mak and colleagues

  2019-07-24

  

  As demonstrated by Mak and colleagues, ERβ is known to be a part of the NFκB-HIF-1α signaling pathway during hypoxia as well as chronic inflammation of prostate (Mak et al., 2015), therefore in the next part of the study, we evaluated whether ZEA-induced ROS production is also associated with NFκB-

• br Phenotypic responses alkylation induced cell death

  2019-07-24

  

  Phenotypic responses: alkylation-induced cell death and mutagenesis E. coli alkB mutants were isolated in a screen for strains specifically sensitive to the cytotoxicity of MMS but not UV-irradiation. This was the first indication that the AlkB protein is a primary cellular defence against alkyla

• Introduction Formate dehydrogenase enzymes FDHs

  2019-07-24

  

  Introduction Formate dehydrogenase enzymes (FDHs) are a group of heterogeneous proteins that catalyse the reversible formate () oxidation to carbon dioxide () (Eq. (1)). These enzymes are classified in two families, one gathering the enzymes that hold no redox-active centres and another that includ

• br Experimental procedures br Introduction Protein

  2019-07-24

  

  Experimental procedures Introduction Protein kinases represent one of the largest enzyme blasticidin in the human genome and act as signaling mediators in a variety of cellular processes (Manning et al., 2002). Because many diseases are associated with aberrant protein kinase activity, targete

• Confirmation of the presence of

  2019-07-24

  

  Confirmation of the presence of H+-PPase genes in the genomes of the different protists tested was obtained by Southern blot analyses using the PCR-amplified DNA fragments as probes (Fig. 3). In the trypanosomatids L. major and T. cruzi and the euglenoid A. longa, a single band appeared in the filte

• Although elevated production of cysLTs is characteristic of

  2019-07-24

  

  Although elevated production of cysLTs is characteristic of rhinosinusitis of diverse etiology, patients with aspirin-sensitive rhinosinusitis show even higher levels of cysLTs in the nasal mucosa, which are further enhanced by aspirin challenge., Elevated production of cysLTs in these patients may

• In this review we first

  2019-07-24

  

  In this review, we first introduce the in vivo metabolism profile of VD3, and the mediation of Cyp3a gene transcription by PXR and CAR in humans, mice and rats. We then focus on the species-specific VDR-dependent regulation of human (CYP3A4, CYP3A5 and CYP3A7), mouse (mainly CYP3A11 and CYP3A13), an

• Methylated CpGs can recruit transcriptional co repressors to

  2019-07-24

  

  Methylated CpGs can recruit transcriptional co-repressors to prevent transcription factors (TFs) from promoting gene expression by tightly packing Exendin-3 (9-39) amide solubility structures [38]. Two CpG islands in the IPT5b promoter region showed higher methylation level in M9 rootstock compared

• br Materials methods br Results and discussion The

  2019-07-23

  

  Materials & methods Results and discussion The comparison of BFI methods (Table 1) shows that Phosphatesmo failed to detect seminal fluid in all samples. This observation is concordant with other studies that investigated water-exposed seminal fluid stains [6], [7]. The Phosphatesmo test is us

• Our results suggest that formation of DDR b clusters may

  2019-07-23

  

  Our results suggest that formation of DDR1b clusters may be important for and precede receptor phosphorylation. Indeed, while DDR1b clustering was readily detected (by YFP signal) 30 min after collagen administration, phosphorylated DDR1 species at Y513 (present in the IJXM) were evident after 4 h

• br Nuclear export and the functions of CRM The nuclear

  2019-07-23

  

  Nuclear export and the functions of CRM1 The nuclear envelope provides a compartmentalized intracellular environment for DNA replication, the synthesis of RNA, and production of ribosomes, and, as such, it can regulate cellular biological processes including apoptosis and proliferation. Nucleocyt

15659 records 969/1044 page Previous Next First page 上5页 966967968969970 下5页 Last page