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To our knowledge immunohistochemical analysis for
2021-08-17

To our knowledge, immunohistochemical analysis for proGRP was done in 5 cases [9], [10], [17], [18]. Takagi-Takahashi et al. reported that the tumor Canrenone synthesis were positive for proGRP in one case [9]. Yamaguchi et al. also showed that tumor cells in two patients of ES/PNET with elevated s
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br Experimental Procedures br Author
2021-08-17

Experimental Procedures Author Contributions Acknowledgments Introduction Estrogen-related receptors (ERRα, ERRβ, and ERRγ) are orphan nuclear receptors whose physiological ligands have not yet been identified. Although ERRs are closely related to estrogen receptors (ERs) they do not res
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ERR is present early in the developing
2021-08-17

ERRβ is present early in the developing placenta in a subset of Ro 48-8071 in extra-embryonic ectoderm destined to make up the chorion.19, 20 ERRβ is likely essential for reproduction. ERRβ expression is essential for the maintenance of pluripotency and self-renewal potential in mouse embryonic ste
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br Ultrasonic pretreatment of substrates Substrate
2021-08-17

Ultrasonic pretreatment of substrates Substrate pretreatment is widely used in the biofuel, textile and food industries since the substrates are always difficult to degrade. During some enzymatic hydrolysis reactions, the protective layer of the substrate impedes the reaction. Ultrasonic treatmen
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More recent studies have correlated sPLA
2021-08-17

More recent studies have correlated sPLA2-V with alternative macrophage activation (M2) in human and murine macrophages [149,150]. sPLA2-V expression was induced during both human and mouse interleukin-4–mediated activation of macrophages in vitro, and its absence impaired macrophage activation in v
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PI K is a lipid
2021-08-17

PI3K is a lipid kinase and generates phosphatidylinositol-(3,4,5)-trisphosphate, which is a second messenger critical for the translocation of Akt to the cytoplasmic membrane. The phosphorylation of Ser473 Akt is important in the cell survival by regulating the eNOS among other targets (Dimmeler et
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VSV-G Peptide Our results from neutropenic mice
2021-08-17

Our results from neutropenic mice infected with both fungal strains revealed that the inflammatory process was more severe 72hours post-infection (Fig. 4). Angioinvasion was mainly observed 48hours after infection for both strains. Transformation of A. fumigatus conidia into hyphae in immunocompeten
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While PRRSV has been recently shown to induce
2021-08-17

While PRRSV has been recently shown to induce SGs, the exact nature of SG formation and its underlying mechanism of regulating antiviral immune response during PRRSV infection remain unclear (Zhou et al., 2017). Formation of PRRSV-induced SGs was observed in MARC145 AZD0156 sale (Chen et al., 2018)
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Similarly in the EAE model Chalmin et
2021-08-17

Similarly in the EAE model, Chalmin et al. previously demonstrated that EBI2 and CH25H might be responsible for the efficient egress of differentiated Th17 cells from the draining lymph nodes [31]. As discussed above, in active EAE we did not find differences in EAE development and only the transfer
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br Acknowledgments This work was supported
2021-08-17

Acknowledgments This work was supported by a grant from the National Center for GM Crops (PJ008152) of the Next Generation BioGreen 21 Program funded by the Rural Development Administration, Republic of Korea, to W.T.K. Introduction Ubiquitin (Ub) has been considered as one of the most import
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CPG a metalloenzyme derived from
2021-08-16

CPG2, a metalloenzyme derived from sp., was the elected enzyme for the first pilot-scale clinical trial of ADEPT. This enzyme has no mammalian homologue and activates glutamic Fmoc-Gly-OPfp prodrug derivatives of several nitrogen mustards alkylating agents., , , , , A bond cleavable by CPG2 is es
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In ER group Histopathological examination followed by Fluore
2021-08-16

In ER + group, Histopathological examination followed by Fluorescence in situ hybridization (FISH) had revealed the absence of HER2 receptors. Co-targeting of ER and HER2 appears to provide benefit without a significant increase in toxicity although formal trials have not been carried out [18]. Adop
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Tibolone is also efficacious on
2021-08-16

Tibolone is also efficacious on bone in elderly women and induces a clear reduction in bone turnover markers [50], [51]. Rymer et al. showed that, after 10 years of treatment with tibolone, the difference in bone mineral density compared with a placebo group was more than 12% for both lumbar spine a
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pannexin-1 inhibitor The work described by Dong Groves
2021-08-16

The work described by Dong, Groves, and co-workers (11) tested the hypothesis that neural stem cell development is sensitive to the clustering and mechanical state of the EphB4:ephrin-B2 receptor-ligand complex. They show that the quality of ephrin-B2-ligand signaling depends on its biophysical stat
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br Concluding remarks br Transparency document br
2021-08-16

Concluding remarks Transparency document Acknowledgements Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under award number P30CA033572 (RS). The content is solely the responsibility of the authors and does not neces
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