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EHT 1864 br Results br Discussion Genomic instability is
2018-10-24
Results Discussion Genomic instability is one of the biggest concerns in the potential clinical use of iPSCs (Rocha et al., 2013). The challenging field of regenerative medicine requires an in-depth understanding of the causes and consequences of genetic abnormalities that arise during the rep
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Regulatory immune cell therapy including regulatory T
2018-10-24
Regulatory immune cell therapy, including regulatory T cells (Tregs) (Bradley, 2014; McMurchy et al., 2011), regulatory dendritic pde inhibitors (DCregs) (Ezzelarab and Thomson, 2011; Moreau et al., 2012), and immature DCs (iDCs) (Roncarolo et al., 2001), is an emerging strategy for the prevention
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The C terminal sequence is crucial for maintaining the struc
2018-10-24
The C-terminal sequence 209–223 is crucial for maintaining the structure of the active site, with its deletions leading to loss of the ligand-binding properties [49]. The carboxyl terminus of the first transmembrane domain TM1 is also involved in the formation of the binding site through close inte
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was introduced for convenience of analysis where are the
2018-10-24
was introduced for convenience of analysis, where are the layer thickness values in dimensional units Two groups of phonon modes (I and II) can be identified in the obtained solutions. These modes have the following frequencies: The first type of solutions deals with the phonons of A(LO) and E(
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br Conclusion SFP was delivered with
2018-10-24
Conclusion SFP 10–14 was delivered with good overall fidelity. Levels of adherence to programme content were high, though with some variation. Delivery of the intervention within the context of an RCT reduced levels of potential among some referrers, affecting the feasibility of planned recruitme
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order EVP-6124 We address this problem from
2018-10-24
We address this problem from a computational modeling point of view, and build an ABM that simulates the outcomes of different targeting methods including selected realistic factors that may interact. There exists a limited but rapidly developing literature for modeling social influence on obesity p
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The Post Keynesian theory of
2018-10-23
The Post Keynesian theory of the banking firm, originally developed by Oreiro (2004) and Silva and Oreiro (2007), advances in the analysis of the determinants of bank spread in Brazil as it demonstrates that “a permanent toward of banking spreads can be obtained through a policy of lower interest r
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In recent years several groups have attempted
2018-10-23
In recent years several groups have attempted to identify specific signatures to distinguish between tuberculosis and sarcoidosis using transcriptomics or gene expression profilings (Koth et al., 2011; Maertzdorf et al., 2012; Berry et al., 2010). Yet, most of these methods led to the discovery of a
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As an essential nuclear protein associated with the centrome
2018-10-23
As an essential nuclear protein associated with the centromere–kinetochore complex, CENPF plays a critical role in chromosome segregation during mitosis (Dai et al., 2013). Researchers have demonstrated that CENPF is overexpressed in a wide variety of human malignancies including HCC, and CENPF is a
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We have now successfully found a previously unknown family o
2018-10-23
We have now successfully found a previously unknown family of non-platinum-based anticancer compounds (called FMD compounds) as potent antitumor agents for natural targeted chemotherapy without the need of using an antibody to bind to cancer cells. Upon entering normal and abnormal (cancer) cells, t
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br Introduction Arsenic is a well known toxic metalloid and
2018-10-23
Introduction Arsenic is a well-known toxic metalloid, and both a naturally occurring and anthropogenic environmental contaminant (Hughes et al., 2011). As such, arsenic levels are regulated in public drinking water supplies in the US and other countries. In accordance with World Health Organizati
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br Contributors br Declaration of Interests br Acknowledgmen
2018-10-23
Contributors Declaration of Interests Acknowledgments This investigation received financial support from the Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT, PAE-PID-00127, PAE-PICT-207-02332 and PICT-0240 to VEG); University of Buenos Aires (20020100100221 and 20020130100236
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An association between reconstitution of
2018-10-23
An association between reconstitution of CD4 T-cells and impaired lung function, measured as oxygen saturation, has been shown in a murine model for IRIS using Mycobacterium avium (). However, our study investigated the association between paradoxical TB-IRIS, change in MMPs on ART, and pulmonary fu
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br Acknowledgements Conflict of Interest br Financial Suppor
2018-10-23
Acknowledgements Conflict of Interest Financial Support The work was financially supported by a grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) at the National Institutes of Health (grant number R21AA023521-01A1 to MR). The sponsor of the study (NIAAA) had no role in
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We sought to further investigate
2018-10-23
We sought to further investigate the phenomenon of amoxicillin/clavulanate susceptibility using comparative genomics. A phylogenetic analysis indicated that a large proportion of MDR and XDR isolates in our dataset were part of a LAM4 clade, which was responsible for the famed Tugela Ferry XDR outbr
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