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Human p MAPK is stimulated by various inflammatory cytokines
2019-04-26
Human p38 MAPK is stimulated by various inflammatory cytokines and cellular stresses [46]. Especially, the p38 MAPK signaling pathway is a crucial modulator of proinflammatory cytokine biosynthesis at the transcriptional and translational levels [46]. Furthermore, studies revealed that p38 MAPK regu
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Some patients developed osmotic demyelination disease
2019-04-26
Some patients developed osmotic demyelination disease (ODS) after rapid correction of hyponatremia. Predisposing factors to development of ODS were syndrome of inappropriate antidiuretic hormone, alcoholism, liver cirrhosis, liver transplantation, renal failure, burns, malnutrition, or neoplasm. Oth
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In an effort to determine whether the primary tumour
2019-04-26
In an effort to determine whether the primary tumour might be responsible for “fertilising” the bone “soil” ready for the cancer “seed”, we recently found that a hypoxic gene signature, and more specifically the secreted enzyme lysyl oxidase (LOX) was closely associated with bone metastasis, specifi
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Cerrone et al reported that the mechanism of CPVT was
2019-04-26
Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje
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Juan Tovar dramaturgo y cr tico teatral presenta en
2019-04-26
Juan Tovar, dramaturgo y crítico teatral presenta en su texto “Los siete géneros”, la teoría que aprendió durante su paso por las aulas de la maestra Luisa Josefina Hernández y cuyas lecciones no obstante su continuo estudio y aplicación por directores y actores en talleres y escuelas de teatro, no
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Perteneciente a la representaci n
2019-04-26
Perteneciente (-)-JQ1 la representación que Hanumān realiza del , Acosta emplea un apto neologismo, el de “hu-mono” (171). Con este término se enfatiza hasta qué punto el narrador y el mono son reflejos el uno del otro. El salto físico del mono gramático inspira otros saltos en el lenguaje de Paz.
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In the trial by Arrossi and colleagues
2019-04-26
In the trial by Arrossi and colleagues in Argentina, purchase (S)-Crizotinib health workers randomly allocated to the intervention group delivered self-collection kits to women at their homes during routine visits, instructed women on how to obtain a cervicovaginal sample for HPV testing, and trans
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En ambos conjuntos hay animales comunes debido a
2019-04-26
3. En ambos conjuntos hay animales comunes debido a su apariencia física, aunque sus conductas y propiedades difieren en forma notable. Es el caso del pelícano, mono, cocodrilo, camaleón, venado, bisonte, lobo, perro, sirena, etc. Otros más tienden a ser confundidos mediante una asimilación comparat
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O processo de sele o crucial
2019-04-26
O processo de seleção é crucial, pois auda ‘escolhida’ será a responsável, nos próximos cinco anos, pela gestão do hospital determinado, decisão publicada em Diário Oficial. Dois aspectos são merecedores de atenção. Inicialmente, a decisão unilateral de escolha pelo Secretário de Saúde por determina
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br For more than a decade WHO has focused
2019-04-26
For more than a decade, WHO has focused its efforts against infectious diseases in Africa on HIV, tuberculosis, and malaria. HIV benefited from unprecedented efforts to enable diagnosis and prevention of transmission and to provide therapy at low cost. National networks of health clinics, transpo
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br Case An year old man with no history
2019-04-26
Case 1 An 81-year-old man with no history of muscarinic receptor antagonists disease was admitted to our hospital for the treatment of recurrent episodes of syncope after drinking. He experienced the first episode at age 75. On admission, his blood pressure (BP) was 144/81mmHg and the heart rate
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br Conclusion br Financial support This research was
2019-04-26
Conclusion Financial support This research was supported by a grant from the ׳Gerencia de Salud, Consejería de Sanidad, Junta de Castilla y Leon׳ [GRS 308/A/08] and ‘Caja Burgos Foundation’ [Convocatoria 2007].The funding organization had no involvement in the study. Clinical trial registr
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br Conflict of interest br Introduction Over the
2019-04-26
Conflict of interest Introduction Over the last several decades, substantial research interest has been focused on characterizing the pathophysiological substrate underlying atrial fibrillation (AF) [1]. AF is a complex arrhythmia and has been shown to be temporally variable, so that AF durati
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Entre los cronistas y sin dejar atr s esta concepci
2019-04-25
Entre los cronistas, y sin dejar atrás esta concepción de la naturaleza y sin que se perciba un mayor conflicto, se advierte, en mayor o menor medida, un acentuado interés por los seres naturales y las “causas segundas”. La razón de esta falta de conflicto frontal obedece, por un lado, al reconocimi
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Wnt-C59 In our study ES SCLC patients in
2019-04-25
In our study, ES-SCLC patients in the CIT group were on average older than those in the control group. However, the multivariate analysis showed that age had no effect on the prognosis of these patients. Therefore, age was no a confounding factor, although it has been reported that effector cell fun
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