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Introduction The heart beat provides the mechanical force
2019-04-16
Introduction The heart beat provides the mechanical force for the pumping of oxygenated blood to, and deoxygenated blood away from, the peripheral tissues [1]. This depends critically on the orderly activation and recovery of electrical excitation through the myocardium. Disruptions of this can lea
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In silico prediction software SIFT PolyPhen CADD and other p
2019-04-16
In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com
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The aim of this cross sectional study was
2019-04-16
The aim of this cross-sectional study was to investigate the relationships between patient characteristics and antithrombotic therapy prescribed for the prevention of ischemic stroke and systemic embolism in patients with NVAF in clinical practice. Additionally, because the data were to be used to c
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An urgent need therefore exists for ministries
2019-04-16
An urgent need therefore exists for ministries of health to introduce programmes for the primary and secondary prevention of rheumatic focal adhesion kinase inhibitor disease through their non-communicable disease programmes. The delivery of penicillin for the treatment of sore throat in children a
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adenosine receptor It s springtime for surgery declared
2019-04-16
“It\'s springtime for surgery!” declared Meena Cherian at the launch of the at the end of April. It certainly seems so. In a few days\' time, WHO Member State representatives will gather at the 68th World Health Assembly to discuss, among other things, the adoption a on surgical care and anaesthes
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Volvemos nosotros a tomar el
2019-04-16
Volvemos nosotros plk1 inhibitor tomar el hilo. El proyecto en cuestión remonta a las de Michel chevalier, publicadas en París en 1836, y que ya circulaban en chile al menos desde 1842. Para la llegada de Bilbao a Francia en 1845, el libro de chevalier era todo un éxito editorial. Había alcanzado e
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There was a modest excess risk of mortality associated with
2019-04-15
There was a modest excess risk of mortality associated with multidrug-resistant organisms, which was lower than that previously recorded in south Asia. There are methodological challenges in the attribution of excess neonatal mortality with antimicrobial resistance because of known confounding with
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Many of the emerging non
2019-04-15
Many of the emerging non-vaccine serotypes in carriage after PCV13 implementation (11A, 15B/C, 15A, 21, 23B, and 35F) show low potential for causing invasive disease, but some—eg, 12F, 22F, 24F, 8, and 9N—have high disease potential. Moreover, in vulnerable populations (eg, immunocompromised people)
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We have recently investigated the role of
2019-04-15
We have recently investigated the role of the p38 MAPK pathway in heat shock-, osmotic shock-, or microwave irradiation-induced neurite outgrowth of PC12m3 get the job [[16], [17], [18]]. When cultures of PC12m3 cells were exposed to heat and osmotic stress or microwave irradiation, activity of p38
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br Discussion and outstanding questions Reproductive endocri
2019-04-15
Discussion and outstanding questions Reproductive endocrine hormones such as inhibin affect breast cancer cell survival in the primary tumour and affect tumour homing and survival in the bone microenvironment. The molecular mechanism driving this effect of hormones in bone is likely to be multif
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At the mechanistic level our results strongly
2019-04-15
At the mechanistic level, our results strongly suggested that the cholestatic protective effect of STS was most likely accounted for by the activation of LXR, a nuclear receptor known for its anti-cholestatic activity. The activation of LXR was supported by the induction of typical LXR target genes,
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A first step is reconsideration of the term family planning
2019-04-15
A first step is reconsideration of the term family planning. This debate is not simply a question of semantics—language is a powerful ideological and political statement. Discourse creates a representation of the world; it perpetuates a cultural and social reality. In this sense, language is action,
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Introduction Despite advances in the treatment of early stag
2019-04-11
Introduction Despite advances in the treatment of early stage breast cancer, bone remains the most common site of distant Epinephrine Bitartrate [1]. The consequences of bone metastases include reduced survival, morbidity, pain and reduced quality of life [2]. While the care of these patients is m
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dihydroergotamine Emergency care inherently addresses the wi
2019-04-11
Emergency care inherently addresses the wide array of illness and injury, including traumatic injuries, surgical disease, acute complications of chronic illness (eg, strokes, myocardial infarction, diabetic ketoacidosis, complications of HIV, tuberculosis, hepatitis C, and other chronic infections),
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En la gr fica se observa que el crecimiento econ
2018-11-15
En la gráfica 9 se observa que el crecimiento económico salubrinal nivel mundial se ha recuperado muy lentamente y que las economías emergentes han desacelerado su crecimiento, el crecimiento mundial parece situarse en 3.5 para este año, similar al de la ocde y de los brics. La crisis de 2009 fue má
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